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03/28/2017 08:57 AM
The life-saving treatment that's being thrown in the trash
A few hours before beginning chemotherapy, a man named Chris faces his cellphone camera with a mischievous smile and describes a perfectly absurd milestone at 1.37pm on a Wednesday. "There is no more beautiful moment in a man's life…" he says with puckish glee. Because how can you not laugh when you've been invited to bank your sperm in advance of being "Godzilla-ed" with chemotherapy and radiation, all just four days after being diagnosed with acute myeloid leukaemia at the age of 43 and given a 5 to 15 per cent chance of survival?
03/20/2017 09:53 AM
DNA labels predict mortality
Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity. Life style and environmental factors influence the methylation in the genome. Scientists have already well documented links between the methylation status of specific positions in the genome and cancer as well as other diseases.
03/17/2017 08:25 AM
Evolocumab significantly reduces risk of cardiovascular events
Evolocumab, one of the new targeted PCSK9 inhibitor drugs that has been shown to dramatically lower levels of low-density lipoprotein (LDL), or "bad" cholesterol, also significantly lowers the risk of cardiovascular events in patients with existing heart or vascular disease already on statin therapy, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.
03/14/2017 07:00 AM
African-Americans must be proactive and reactive to fight heart disease
Sixteen years ago, Kinzo Evans was diagnosed with congestive heart failure. His stomach was swollen. At night, he couldn't lay prostrate to sleep because it was hard for him to breathe. He was also fatigued. Evans' deteriorating condition eventually necessitated a heart transplant, which he had at VCU Health in December 2016.
03/02/2017 12:41 PM
New eczema drug promising in early trial
(HealthDay)—An experimental drug may significantly reduce the itching and improve the appearance of moderate to severe eczema, a new, preliminary trial finds.
03/01/2017 10:42 AM
Highly prevalent gene variants in minority populations cause kidney disease
African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2—in APOL1, a gene that codes for a human-specific protein. However, direct evidence showing that these variants definitively cause kidney disease was lacking because APOL1 is widely expressed in different cell types but the gene is present in only some primates and humans. The challenge has been to create an animal model to prove this. Now, a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania has engineered mice with these mutations that cause human-like kidney disease.
02/23/2017 08:49 AM
Direct-to-consumer genomics: Harmful or empowering?
Thanks to recent scientific advances and plunging costs in genetic sequencing, consumers now can order simple, inexpensive, mail-in genetic tests to learn more about health risks, inherited traits and ancestry. But, is it a good idea to bypass your doctor's office when it comes to interpreting health risks?
02/09/2017 04:50 PM
Emflaza approved for duchenne muscular dystrophy
(HealthDay) —Emflaza (deflazacort) has been approved by the U.S. Food and Drug Administration to treat Duchenne muscular dystrophy in people five years and older, the agency said Thursday in a news release.
02/01/2017 07:26 AM
An impulsive cognitive style comes with implications, researchers say
Know anyone who would rather have $40 right now than $80 next month? Psychology researchers have just published a sprawling study about such folks. It shows them to have a mild but consistent set of tendencies—the scientists call it a "surprisingly broad cognitive phenotype"—to take the quicker and simpler path when thinking about logical challenges, the people around them, the societies they live in and even spiritual matters.
01/19/2017 02:59 AM
Know the risks, warning signs of ovarian cancer
(HealthDay)—Women need to be aware their risk for ovarian cancer increases with age. Half of all cases affect women age 63 or older, according to specialists at Fox Chase Cancer Center in Philadelphia.
11/03/2016 12:00 PM
Why bad genes aren't always bad news
We usually think of mutations as errors in our genes that will make us sick. But not all errors are bad, and some can even cancel out, or suppress, the fallout of those mutations known to cause disease. Little is known about this process—called genetic suppression—but that's about to change as University of Toronto researchers begin to lay out the general rules behind it.