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12/05/2017 12:47 PM
In multiple myeloma, high levels of enzyme ADAR1 are associated with reduced survival
Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1. Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.
11/17/2017 01:44 AM
New study further supports use of progesterone to fight preterm birth (Update)
A new study published today - World Prematurity Day - in the American Journal of Obstetrics & Gynecology provides additional support for treatment with vaginal progesterone to reduce the risk of preterm birth, neonatal complications and infant death in pregnant women with a short cervix. A shortened cervix is the most powerful predictor of preterm birth.
11/15/2017 01:30 PM
Mepsevii approved for rare enzyme disorder
(HealthDay)—Mepsevii (vestronidase alfa-vjbk) has been approved by the U.S. Food and Drug Administration to treat a rare, genetic disorder called mucopolysaccharidosis type VII, sometimes called Sly syndrome.
11/13/2017 02:45 PM
Research advances understanding of opioid addiction in face of public health crisis
As the United States grapples with the devastating effects of an opioid epidemic, researchers are making progress in advancing our understanding of opioid addiction-related health issues, according to studies presented today at Neuroscience 2017, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
11/12/2017 12:24 PM
Innovative genetic and cellular techniques help identify multiple disease targets
Research released today highlights advances in the use of CRISPR-Cas9 and human induced pluripotent stem cell technologies to identify novel therapeutic targets for neurological disorders such as schizophrenia and addiction. The studies were presented at Neuroscience 2017, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
11/10/2017 07:00 AM
The mystery of a 1918 veteran and the flu pandemic
Vaccination is underway for the 2017-2018 seasonal flu, and next year will mark the 100-year anniversary of the 1918 flu pandemic, which killed roughly 40 million people. It is an opportune time to consider the possibility of pandemics – infections that go global and affect many people – and the importance of measures aimed at curbing them.
11/07/2017 09:20 AM
If we can beat Ebola, why not sleeping sickness too?
The man sits on the edge of the bed, feet touching the floor but incapable of supporting his weight. He doesn't speak and his eyes stare vacantly ahead, despite the eight or ten people who have crowded in to see him. His mother stands nearby, beside herself with despair. He's had these symptoms for a year, she tells us. His brother has to carry him on his back at home in their village.
10/25/2017 07:58 AM
The downside of knowing too much about our genes
Self-knowledge is a goal greatly prized by mystics and philosophers. However, too much knowledge about one's own genes can lead to some adverse psychological consequences, two new Yale-led research projects have found.
10/24/2017 04:10 PM
Genetics may put a person at risk of high triglycerides, but adopting a healthy diet can help
Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome—a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist. People with metabolic syndrome have increased risk for heart disease, diabetes, and stroke.
10/13/2017 08:10 AM
Five persistent myths about the causes of breast cancer
Understanding what causes a type of cancer is vital to prevent more cases in the future. But it can feel like we're being told to avoid a new thing every day because it might cause cancer. A survey in the US found that agreement with the phrase: "It seems like everything causes cancer" is on the increase – even though, thanks to research, we know more about what causes and prevents cancer than ever before.
10/11/2017 09:01 AM
How parents can conquer guilt to help kids with eating disorders
Lydia is seriously underweight and suffering from medical complications from an eating disorder. She is in hospital. Her treatment team recruits her mom to help Lydia gain weight through meal support. Lydia and her mom sit down for their first meal together.
10/09/2017 03:00 PM
Alzheimer's gene poses both risk and benefits
Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially raise a person's risk of the disease. The bad news is that in the early stages of the disease, high-risk TREM2 variants can hobble the immune system's ability to protect the brain from amyloid beta, a key protein associated with Alzheimer's.
10/06/2017 08:43 AM
Antisocial behaviour mainly a consequence of gene interactions
Individual genes have little influence in the development of antisocial behaviour. However, the interaction of genes as a whole could explain some of the differences in antisocial behaviour. This was revealed by international research among more than 25,000 participants in which the researchers Jorim Tielbeek, Arne Popma, Tinca Polderman and Danielle Posthuma of VUmc and VU Amsterdam were involved. Tielbeek carried out this research with funding from the NWO programme Research Talent. The research was published today in JAMA Psychiatry.
10/05/2017 12:53 PM
Genomic screening helps doctors target girl's cancer
Victoria Thompson, clutching a bag of salt and vinegar potato chips while she watches the TV show "Paw Patrol," is a pint-sized pioneer. She doesn't know it, but this two-year-old girl is part of a national precision medicine trial through MUSC Children's Health for children with high-risk neuroblastoma.
10/03/2017 03:40 PM
Breast cancer's decline may have saved 322,000 lives
(HealthDay)—New research finds the number of American women who've lost their lives to breast cancer has fallen precipitously in the past 25 years, with more than 322,000 lives saved in that time.